Story ideas
The Little Ice Age in Europe
Cool, wet summers led to outbreaks of an illness called St. Anthony's Fire. Whole villages would suffer convulsions, hallucinations, gangrenous rotting of the extremities, and even death. Grain, if stored in cool, damp conditions, may develop a fungus known as ergot blight and also may ferment just enough to produce a drug similar to LSD. (In fact, some historians claim that the Salem, Massachusetts witch hysteria was the result of ergot blight.)
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Link found via: Risky Regencies

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